Gregg B Fields Selected Research

Therapeutics

2/2023	Screening MT1-MMP Activity and Inhibition in Three-Dimensional Tumor Spheroids.
1/2019	A Novel Probe for Spliceosomal Proteins that Induces Autophagy and Death of Melanoma Cells Reveals New Targets for Melanoma Drug Discovery.
1/2018	The RUNX1/IL-34/CSF-1R axis is an autocrinally regulated modulator of resistance to BRAF-V600E inhibition in melanoma.
1/2017	The Roles of Matrix Metalloproteinases in Pancreatic Cancer.
2/2015	A Peptide mimicking a region in proliferating cell nuclear antigen specific to key protein interactions is cytotoxic to breast cancer.
2/2008	Screening of potential a disintegrin and metalloproteinase with thrombospondin motifs-4 inhibitors using a collagen model fluorescence resonance energy transfer substrate.

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Gregg B Fields Research Topics

Disease

40	Neoplasms (Cancer) 01/2024 - 04/2003
17	Melanoma (Melanoma, Malignant) 01/2019 - 05/2002
7	Rheumatoid Arthritis 01/2023 - 03/2014
7	Osteoarthritis 11/2022 - 01/2008
6	Neoplasm Metastasis (Metastasis) 02/2023 - 10/2003
6	Arthritis (Polyarthritis) 01/2023 - 10/2003
5	Breast Neoplasms (Breast Cancer) 01/2021 - 04/2013
4	Fibrosis (Cirrhosis) 01/2022 - 09/2014
4	Inflammation (Inflammations) 01/2019 - 05/2007
3	Disease Progression 01/2015 - 09/2009
2	Alzheimer Disease (Alzheimer's Disease) 02/2024 - 08/2014
2	Cachexia 01/2022 - 01/2020
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 09/2012
2	Sepsis (Septicemia) 11/2019 - 11/2017
2	Periodontal Diseases (Periodontal Disease) 01/2019 - 08/2009
2	Myocardial Infarction 11/2016 - 09/2015
2	Neuroblastoma 12/2015 - 01/2014
1	Amyloid Plaque 02/2024
1	Prostatic Diseases 06/2023
1	Prostatic Neoplasms (Prostate Cancer) 06/2023
1	Glioma (Gliomas) 02/2023
1	Autoimmune Diseases (Autoimmune Disease) 01/2023
1	Experimental Arthritis 01/2023
1	Chronic Disease (Chronic Diseases) 05/2022
1	Fragile X Syndrome (Martin Bell Syndrome) 01/2022
1	Acute-Phase Reaction 01/2022
1	Osteolysis 01/2021
1	Adenocarcinoma of Lung 01/2021
1	Multiple Myeloma 01/2021
1	Carcinoma (Carcinomatosis) 12/2020
1	Diabetic Foot 01/2019
1	Multiple Sclerosis 01/2019
1	Stomach Neoplasms (Stomach Cancer) 01/2019
1	Ulcer 01/2019

Drug/Important Bio-Agent (IBA)

23	Matrix Metalloproteinases (MMPs)IBA 01/2024 - 05/2003
19	CollagenIBA 02/2023 - 04/2003
10	Peptides (Polypeptides)IBA 02/2024 - 10/2004
10	Peptide Hydrolases (Proteases)FDA Link 01/2024 - 05/2003
9	Proteins (Proteins, Gene)FDA Link 02/2024 - 09/2008
9	Matrix Metalloproteinase 14 (MT1-MMP)IBA 01/2024 - 04/2013
9	Metalloproteases (Metalloproteinases)IBA 02/2021 - 10/2004
6	Matrix Metalloproteinase InhibitorsIBA 02/2023 - 03/2012
6	Matrix Metalloproteinase 13IBA 01/2021 - 01/2008
6	Collagen Type IV (Type IV Collagen)IBA 08/2014 - 05/2002
6	LigandsIBA 01/2007 - 05/2002
5	IntegrinsIBA 01/2022 - 04/2003
5	EnzymesIBA 01/2021 - 06/2004
4	Collagen Type II (Type II Collagen)IBA 01/2023 - 11/2020
3	AutoantibodiesIBA 01/2023 - 11/2020
3	ZincIBA 02/2021 - 09/2014
3	Tiopronin (Thiola)FDA Link 02/2021 - 09/2014
3	Proteoglycans (Proteoglycan)IBA 07/2017 - 05/2002
3	Proliferating Cell Nuclear Antigen (PCNA)IBA 12/2015 - 01/2014
3	GelatinasesIBA 08/2014 - 03/2012
3	Liposomes (Liposome)IBA 01/2012 - 01/2007
2	Amyloid (Amyloid Fibrils)IBA 02/2024 - 08/2014
2	AntibodiesIBA 01/2023 - 11/2022
2	Arginine (L-Arginine)FDA Link 11/2022 - 02/2015
2	ProteomeIBA 01/2022 - 01/2020
2	2-Oxoglutarate 5-Dioxygenase Procollagen-Lysine (Lysyl Hydroxylase)IBA 01/2021 - 12/2016
2	Matrix Metalloproteinase 9 (Gelatinase B)IBA 11/2016 - 11/2014
2	Protein Isoforms (Isoforms)IBA 02/2015 - 01/2014
2	DisintegrinsIBA 03/2014 - 01/2007
2	Laminin (Merosin)IBA 07/2008 - 08/2007
2	Chondroitin Sulfate ProteoglycansIBA 04/2007 - 04/2003
2	Cell Surface ReceptorsIBA 01/2007 - 12/2004
2	Integrin alpha2beta1IBA 12/2004 - 10/2004
1	Amyloid beta-PeptidesIBA 02/2024
1	CytokinesIBA 06/2023
1	HydrogelsIBA 02/2023
1	neutrophil cytosolic factor 1IBA 05/2022
1	Monoclonal AntibodiesIBA 05/2022
1	MannansIBA 05/2022
1	LipidsIBA 01/2022
1	NAD (NADH)IBA 01/2022
1	Biomarkers (Surrogate Marker)IBA 01/2022
1	Mitogen-Activated Protein KinasesIBA 01/2022
1	FibrinIBA 01/2022
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2022
1	Collagen Type VIIBA 01/2022
1	UDP glucose-collagen glucosyltransferase (procollagen glucosyltransferase)IBA 01/2021
1	Mucin-1 (CA 15-3 Antigen)IBA 12/2020
1	GlycopeptidesIBA 12/2020
1	Galectin 1 (LGALS1)IBA 12/2020
1	Thomsen-Friedenreich antigenIBA 12/2020
1	SolutionsIBA 12/2020
1	AntigensIBA 12/2020
1	glycosylated collagenIBA 07/2020
1	Acyl Coenzyme A (Acyl CoA)IBA 01/2020
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2020
1	Adenosine Triphosphate (ATP)IBA 01/2019
1	RNA Helicases (RNA Helicase)IBA 01/2019
1	Heterogeneous-Nuclear Ribonucleoproteins (Informatin)IBA 01/2019
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2019
1	CytosineIBA 01/2018

Therapy/Procedure

6	Therapeutics 02/2023 - 02/2008
1	Castration 06/2023
1	Injections 05/2022
1	Intravenous Injections 05/2022
1	Immunotherapy 01/2019